Dr. Windle’s research is focused on bioinformatic approaches to studying head and neck cancer. One area of research is the study of the mechanisms of HPV-mediated oncogenesis, and the associated gene amplification and mutation events, using high throught-put sequencing and genomics. View Full Profile
Work in the Grossman Lab is focused in 3 areas: 1) Regulation of the p53 tumor suppressor by the ubiquitin/proteasome system. We have identified novel factors that modulate p53 stability, such as the coactivators p300/CBP, and the tumor suppressor DBC1 (Cell Reports 2019 26:3323) with the goal of restoring p53 stability and tumor suppressor activity in tumors that retain a wild type p53 allele.See More
The Harada lab is focusing on the regulatory mechanisms of cell death, which are important for tumorigenesis and the response to a variety of chemotherapeutic drugs. See More