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Dr. Sumitra Deb

Dr Deb's publications.

  1. Lanyi A, Deb D, Seymour RC, Ludes-Meyers JH, Subler MA, Deb S. 'Gain of function' phenotype of tumor-derived mutant p53 requires the oligomerization/nonsequence-specific nucleic acid-binding domain. Oncogene. 1998; 16:3169. PMID: 9671396.
  2. Scian MJ, Stagliano KE, Ellis MA, Hassan S, Bowman M, Miles MF, Deb SP, Deb S. Modulation of gene expression by tumor-derived p53 mutants. Cancer Res. 2004; 64:7447. PMID: 15492269.
  3. Vaughan CA, Deb SP, Deb S*, Windle B*. Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites. Oncotarget, 5: 417-422, 2014. PMCID: PMC3964217.
  4. Vaughan CA, Pearsall I, Singh S, Windle B, Deb SP, Grossman SR, Yeudall WA, Deb S. Addiction of lung cancer cells to GOF p53 is promoted by up-regulation of epidermal growth factor receptor through multiple contacts with p53 transactivation domain and promoter. Oncotarget. 2016 Mar 15; 7:12426-12446, 2016.
  5. Singh S, Vaughan C, Frum R, Grossman S*, Deb S*, Deb SP*. Mutant p53 establishes targetable tumor dependency by promoting unscheduled replication. Journal of Clin. Inves. 2017 May 1;127(5):1839-1855. doi: 10.1172/JCI87724.
  6. Vaughan CA, Singh S, Windle B, Yeudall WA, Frum R, Grossman SR, Deb SP, Deb S. Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase Axl. Genes Cancer. 3:491-502, 2012. PMID: 23264849 PMCID: PMC3527987
  7. Vaughan CA, Singh S, Grossman SR, Windle B, Deb SP, Deb S. Gain-of-function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cells. Mol Oncol. 2017 Jun;11(6):696-711. PMCID: PMC5467493
  8. Vaughan CA, Singh S, Subler, MA, Windle, JJ, Inoue, K, Fry, EA, Grossman SR, Windle B, Yeudall WA, Deb SP, Deb S. Recruitment of PLK3 by tumor-derived mutant p53 to enhance its oncogenicity. Nature Commun. In revision, 2020

Complete List of Published Work is available in MyBibliography: here